10 Non-Human Isekai Anime Characters You Should Know

10 Non-Human Isekai Anime Characters You Should Know

Isekai anime characters are celebrated for their journeys to enchanting realms, often acquiring remarkable abilities along the way. While most protagonists are human, several characters defy this convention by taking on entirely different forms, including reincarnated monsters, divine beings, and mythical entities.

These characters are captivating not only because they stray from the typical human protagonists but also due to their unique origins and powers. Whether they are born as slimes, wolves, or even undead lich kings, their distinct attributes enrich the isekai world, allowing them to navigate new environments in ways that human characters cannot. Here are ten notable Isekai anime characters who are not humans.

Tohru, Aqua, and 8 More Isekai Anime Characters Who Are Not Humans

1) Ainz Ooal Gown (Overlord)

Ainz Ooal Gown as seen in anime (Image via Studio Madhouse)
Ainz Ooal Gown from Overlord (Image via Studio Madhouse)

Ainz Ooal Gown, the protagonist of Overlord, begins as a human player trapped within the virtual realm of Yggdrasil. Once transported to this world, he assumes the form of his in-game avatar, an undead lich king. As a lich, he lacks human emotions and does not require sleep or sustenance. Furthermore, he wields immense magical prowess.

This metamorphosis into an undead being significantly alters his interactions with others, particularly humans, whom he views from a detached perspective. Ainz Ooal Gown stands out as one of the popular isekai anime characters who are not human.

2) Raphtalia (The Rising of the Shield Hero)

Raphtalia as seen in anime (Image via Kinema Citrus)
Raphtalia from The Rising of the Shield Hero (Image via Kinema Citrus)

Raphtalia is a demi-human raccoon-type therianthrope featured in The Rising of the Shield Hero. She possesses a blend of human and animal characteristics, including a fluffy tail and enhanced physical attributes. Raphtalia fights fiercely alongside Naofumi, owing to her demi-human traits, which augment her agility and combat abilities.

Unlike typical humans, she ages based on her experiences, maturing rapidly according to her level. Her unique heritage and non-human nature significantly influence her development and relationships, establishing her as one of the isekai anime characters who are not human.

3) Rimuru Tempest (That Time I Got Reincarnated as a Slime)

Rimuru Tempest as seen in anime (Image via 8bit)
Rimuru Tempest in That Time I Got Reincarnated as a Slime (Image via 8bit)

The protagonist of That Time I Got Reincarnated as a Slime, Rimuru Tempest, starts off as an ordinary human but is reborn as a lowly slime monster in a fantastical world. Despite this modest form, Rimuru overcomes formidable opponents and rivals, leveraging their unique abilities and skills.

As the story progresses, Rimuru evolves into a powerful leader, transitioning into more complex beings while retaining their non-human identity. This evolution is central to their role, making them a prominent example of isekai anime characters who do not possess a human identity.

4) Tohru (Miss Kobayashi’s Dragon Maid)

Tohru as seen in anime (Image via Kyoto Animation)
Tohru from Miss Kobayashi’s Dragon Maid (Image via Kyoto Animation)

Tohru is one of the central female protagonists in Miss Kobayashi’s Dragon Maid, hailing from a world of dragons. She has the ability to transform into human form and begins her journey after crossing paths with Miss Kobayashi, taking on the role of her maid in the human realm.

While Tohru may appear human, she retains dragon-like qualities, such as immense strength, the ability to breathe fire, and her transformation capabilities. Her non-human origins and magical abilities place her among the intriguing isekai anime characters who are not human.

5) Zero (Grimoire of Zero)

Zero as seen in anime (Image via White Fox)
Zero from Grimoire of Zero (Image via White Fox)

In Grimoire of Zero, Zero is a powerful witch who possesses unparalleled mastery over magic, transcending the typical capabilities of a human. She has an extensive understanding of ancient magic and can cast spells most others cannot grasp.

Her origins and abilities make her more of a mystical figure than an ordinary human, as she travels the world in search of a lost grimoire with her beastly companion. This distinction earns her a spot among the isekai anime characters who are not human.

6) Aqua (KonoSuba)

Aqua as seen in anime (Image via Studio Deen)
Aqua from KonoSuba (Image via Studio Deen)

Aqua, the goddess of water from KonoSuba, despite her divine status, joins Kazuma in the human world after being inadvertently dragged along during his reincarnation. Her abilities include purifying undead creatures and casting powerful healing spells, though she often struggles with practical challenges and depends on her divine status.

This combination places Aqua far from being human while her comedic personality often downplays her godly nature, solidifying her status among the isekai anime characters that are not human.

7) Holo (Spice and Wolf)

Holo as seen in anime (Image via Brain's Base / Marvy Jack)
Holo from Spice and Wolf (Image via Brain’s Base / Marvy Jack)

Holo, known as the wolf god in Spice and Wolf, is famously recognized in folklore as the Wise Wolf of Yoitsu. She takes the appearance of a young woman with wolf ears and a tail, yet in reality, she is a colossal wolf infused with ancient wisdom and supernatural capabilities.

Team-up with a traveling merchant named Lawrence, her intelligence and cunning elevate their adventures. Holo’s dual nature and her ability to shapeshift between human and wolf forms add to her uniqueness, marking her as one of the compelling isekai anime characters who are not human.

8) Fran (Reincarnated as a Sword)

Fran as seen in anime (Image via C2C)
Fran from Reincarnated as a Sword (Image via C2C)

Fran is featured as one of the non-human characters in the anime Reincarnated as a Sword. As a Black Cat, she possesses feline traits such as cat ears and a tail that set her apart from humanity.

Carrying the intelligent sword “Teacher,”Fran embarks on a journey to evolve and break free from her tribe’s limitations. Her exceptional martial arts skills and indomitable spirit establish her as a formidable warrior.

9) Kumoko (So I’m a Spider, So What?)

Kumoko as seen in anime (Image via Millepensee)
Kumoko from So I’m a Spider, So What? (Image via Millepensee)

Kumoko from So I’m a Spider, So What? is recognized as one of the non-human characters in isekai anime. Originally a spider monster named Small Lesser Taratect, her character features a fluffy white body with black spots and eight menacing red eyes.

As she evolves, she transforms into various forms, such as the Zoa Ele with scythe-like claws and the Zana Horowa with a pristine white body. Her ultimate transformation is the Arachne, taking on a hybrid appearance where her upper half resembles a young girl while her lower half merges with a gigantic white spider’s body.

10) Boxxo (Reborn As A Vending Machine, I Now Wander The Dungeon)

Boxxo as seen in anime (Image via Studio Gokumi)
Boxxo from Reborn As A Vending Machine, I Now Wander The Dungeon (Image via Studio Gokumi)

In Reborn as a Vending Machine, I Now Wander the Dungeon, the hero Boxxo presents an intriguing take on non-human isekai characters. After dying, he revives not as a person but as a vending machine in a fantasy universe.

This transformation into an inanimate object introduces both challenges and advantages as Boxxo navigates the dungeon, dispensing items to adventurers. His unique non-human status adds an unusual twist to the isekai genre, securing his place among the isekai anime characters who are not human.

Final Thoughts

The isekai genre frequently subjects its protagonists to extraordinary transformations, diverging from the classic hero narrative centered on a human form. These Isekai anime characters, whether they take the shape of slimes, dragons, or even vending machines, offer fresh perspectives and insights that human characters often cannot access. Their varying backgrounds and abilities enhance the richness of isekai narratives and highlight creativity and variety within the genre.

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