The ending of the original Resident Evil 4 has been altered in the remake, which has significant implications for the future of the series. Warning: Major spoilers ahead for both Resident Evil 4 and its Separate Ways DLC!
The conclusion of the original Resident Evil 4 followed the same pattern as the previous installments in the franchise. The antagonist transforms into a monstrous blob, and the protagonist engages in a fierce battle until obtaining a rocket launcher to defeat the creature. In a typical fashion, the hero delivers a cheesy one-liner like “Game Over”before blasting the enemy. Afterwards, the heroes make their escape on a helicopter/train/jet-ski and pledge to bring down Umbrella or another enemy.
In the remake of Resident Evil 4, everything unfolds as intended, with the added bonus of the game hinting at what’s to come in the series. This is especially evident in the remakes and ties in smoothly with previous installments. Let’s take a look at the events that transpire in the finale of the Resident Evil 4 remake, including the DLC Separate Ways.
Ada Wong has her own agenda in RE4.
Sayonara, Saddler
In a similar fashion to the original Resident Evil 4, the remake concludes with Leon Kennedy successfully saving both Ashley Graham (daughter of the President) and his complicated relationship with Ada Wong from Osmund Saddler, the leader of the Los Illuminados cult. With the help of their now-deceased ally Luis, Leon and Ashley are able to rid themselves of the Las Plagas infection before facing off against the main antagonist.
After successfully disabling Saddler’s mutated form, Ada tosses a rocket launcher to Leon who uses it to deliver a final and fatal blow to the villain. This destroys Saddler’s master Plaga parasite and liberates the Ganados from his control, though it unfortunately results in many casualties. Nevertheless, this outcome may be seen as a preferable alternative to being under his murderous influence.
Instead of resorting to violence and forcing Leon to hand over the virus sample, Ada presents him with a chance to join her on her helicopter and become her partner. However, Leon politely declines and instead, Ada gives him the keys to her jetski as a parting gift. Unbeknownst to Leon, Ada’s true objective was to obtain the Las Plagas sample all along. As Leon and Ashley make their escape on the jetski, Ada watches from her helicopter and ensures their safety.
Assuming that Leon and Ashley have returned home, Leon likely finishes writing ‘The Kennedy Report’ about the incident, which Chris Redfield refers to in RE5.
Ashley and Leon escape together.
A change of heart
After completing her mission to infiltrate Saddler’s cult and steal a sample of the virus/parasites, Ada has a video call with series antagonist Albert Wesker. This is not the first time Ada has interacted with Wesker, as he had previously helped her survive the events of Racoon City and betrayed the Umbrella Corporation. She is aware of his association with their rival company, Tricell. The protagonists, who have also encountered Wesker in the events of Resident Evil: Code Veronica, know that he is still alive and is working with Ada. In the original RE4, Leon even questions Ada’s alliance with Wesker, but the dialogue has been changed in the remake.
After revealing his plan to use Las Plagas and the T-Virus to murder billions of people as part of his Uroboros project, Wesker informs Ada of his intentions. Shocked and appalled, Ada immediately ends the call with the sunglasses-wearing psychopath and takes control of the helicopter, forcing the pilot to fly to a different location at gunpoint. While the original game did not show it, the remake gives us a glimpse of Ada’s betrayal of Wesker before the credits roll.
In the current point of the narrative, both Wesker and Ada are employed by an entity known as “The Agency.”While the S.D. Perry novels suggest that this is the US Government, these books are not considered canon in the game universe. In other sources within the games, The Agency is referred to as H.C.F., a competitor of Umbrella. In recent installments of the series, such as RE7 and Village, the H.C.F. is shown to be collaborating with another group of antagonists known as “The Connections.”This shadowy organization has been involved in bio-weapon research, alongside Mother Miranda, the main antagonist of RE Village. Interestingly, Mother Miranda also served as the mentor of Oswell E. Spencer,
Even though Wesker had previously betrayed The Agency and aligned himself with Tricell, he ultimately double-crossed them in pursuit of his own agenda by the time of Resident Evil 5. It is unclear if Ada remained loyal to The Organization, as she is shown receiving instructions from an unknown source in Resident Evil 6, several years after Wesker’s demise.
Wesker’s plans are hindered by Ada’s betrayal – but not for long.
Explaining the ending of Separate Ways
The Separate Ways DLC expands upon the concluding scene between Ada and Wesker, offering a glimpse into Wesker’s perspective. It is revealed that Wesker had already obtained a sample of the Las Plagas parasites by securing Saddler’s body. In addition to possessing samples of the Progenitor, T, and G Viruses, Wesker now has a Master Plaga at his disposal, giving him the ability to manipulate a population like Saddler and create his powerful Uroboros virus.
Wesker is later shown on a boat, proudly celebrating his victory and dismissing Ada’s betrayal as insignificant. His subordinates suggest attacking her, but he refuses and declares that the “end of humanity is near.”This alludes to his scheme to spread his latest virus worldwide, as seen in Resident Evil 5. This added scene could hint at Capcom’s plans to possibly remake RE5 next, or it could simply be a nod to the events of the game.
What happens next?
In the prequel chapter Lost in Nightmares DLC for Resident Evil 5, Wesker confronts Oswell E. Spencer, a fugitive, about his origins before ultimately killing him. During this encounter, he also runs into his former adversaries, Chris Redfield and Jill Valentine. It is revealed in Resident Evil 5 that Ada did not give the sample to Wesker, but instead gave it to The Agency, the organization that initially hired her. Additionally, Ada managed to lure Wesker and William Birkin, both from Resident Evil 2, into betraying Umbrella.
In the first RE5, Wesker acquired a Las Plagas sample from Ricardo Irving, a former Umbrella researcher. As hinted in the RE3 remake, the T-virus may have contained the parasites as an ingredient, suggesting that Irving and Umbrella had access to it from the beginning.
Wesker uses this discovery to infect the inhabitants of an African village, setting off the chain of events in the game. In the RE4 remake, it is revealed that Luis Sera, a former Umbrella researcher, also played a role in the development of the parasites, further linking them to the T-Virus. This also clarifies the similarities in their mutagenic effects, such as the growth of large eyeballs on the hosts’ limbs.
In RE5, Wesker successfully develops his Uroboros super virus but is ultimately defeated and killed by Chris Redfield, Sheva Alomar, and Jill Valentine at the conclusion of the game.
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